Rejuvenating Complex
Rejuvenating Complex
Rejuvenating Complex
Back of hand showing lightweight anti aging skincare serum texture
Before and after video of woman's progress from using anti-aging skincare
Rejuvenating Complex
Rejuvenating Complex
Regenerative Clinical Skincare

The Rejuvenating Complex

with BioBlend Technology™

Powered by our proprietary BioBlend Technology™, INVO Aesthetics’ Rejuvenating Complex is an all-in-one anti-aging product that delivers a concentrated blend of growth factors, peptides, and exosomes to visibly restore skin vitality, improve tone, and support long-term rejuvenation. 


Clinically formulated to restore cellular signaling and visibly reduce signs of aging.


$285.00 USD
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The same regenerative science used in clinical procedures, formulated for daily use at home.
  • Free Shipping

  • Cruelty-Free

  • Dermatologist-Loved

  • Gluten-Free

  • For All Skin Types

  • 30-day Returns

  • Paraben-Free

Benefits Overview
  • Visibly firms and smooths the skin by stimulating new collagen and elastin production.
  • Reduces the appearance of fine lines and wrinkles.
  • Enhances tone and refines texture for a more radiant complexion.
  • Infused with powerful antioxidants to help protect against future damage.
  • Calms and soothes the skin to reduce redness and irritation.

Key Ingredients

  • BioBlend Technology™: A Sophisticated blend of high-powered growth factors and exosomes proven to enhance facial rejuvenation
  • Peptides: A selective blend of potent peptides that collectively support collagen and elastin production to enhance skin rejuvenation
  • Honeybee Defensin-1: A powerful antimicrobial that boosts skin defenses, promotes healing, reduces inflammation, and improves hydration for a smooth, clear, healthy complexion
  • Niacinamide: Reduces inflammation, brightens skin tone, and improves the barrier function to lock in moisture
  • Carnosine: Protects skin from free radicals, prevents glycation-related collagen damage, and maintains firmness for a youthful, smooth appearance
  • Tetrahexyldecyl Ascorbate (Vitamin C): Brightens skin, stimulates collagen, and defends against free radical damage, without the irritation of traditional Vitamin C. Clinically proven to reduce hyperpigmentation and boost radiance.

How to Use

Apply twice daily (morning and night) to reduce the signs of aging for a more radiant, youthful glow.

Full Ingredients

Water (Aqua), Human Mesenchymal Conditioned Media, Glycerin, Pentylene Glycol, Niacinamide, Cetyl Ethylhexanoate, Dimethyl Isosorbide, Polyacrylate-13, sh-Polypeptide-3, sh-Polypeptide-77, sh-Polypeptide-2, sr-Honey Bee Defensin-1, Palmitoyl Tripeptide-1, Tetrapeptide-14, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, sh-Oligopeptide-1, Superoxide Dismutase, Carnosine, Cetyl Stearate, Polyisobutene, Polysorbate 20, Tetrahexyldecyl Ascorbate, Propanediol, Lecithin, Sodium Hyaluronate, Helianthus Annuus (Sunflower) Seed Oil, Arnica Montana Flower Extract, Acetyl Glutamine, Bacillus/Folic Acid Ferment Filtrate Extract, Caprylyl Glycol, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Dehydroacetic Acid, Phenoxyethanol, Ammonium Sulfate, Tocopherol, Benzyl Alcohol, Citric Acid, Sodium Hydroxide.
1,200+
Growth factors, proteins & peptides
1.2 Trillion
Exosomes
4
key regenerative pathways
8wks
To visible results in clinical observations
The Science, Defined
Designed to work beneath the surface, where renewal begins
Visible aging is a lagging indicator. By the time you see a wrinkle, the cellular decline that caused it has been underway for years. BioBlend Technology™ targets those foundational processes — not just the symptoms.
Cellular communication, not surface coverage
01
Growth factors, peptides, and exosomes act as biological messengers, signaling skin to rebuild collagen, renew elastin, and restore structural integrity. This continuous communication supports skin’s ability to maintain itself over time.
Regenerative pathways,
clinically supported
02
Independent third party evaluations show BioBlend Technology™ supports key pathways including collagen biosynthesis, extracellular matrix organization, and inflammation modulation. These are the same mechanisms targeted in clinical procedures, now integrated into your daily routine.
Derived from three
stem cell sources
03
Multiple cell sources are combined to create a more potent and comprehensive ingredient than any single source can provide. Developed by stem cell PhDs using proprietary methods. Ethically sourced without exception.

Where skincare begins to work differently

Skin is constantly communicating, renewing, adapting. Over time, that communication becomes less precise. Renewal slows. The visible signs follow.

The opportunity is not in adding more. It is in supporting what already exists, at the level where change begins.
Woman-Applies-Rejuvenating-Complex_bc0c7712-e8fd-4336-8e21-bf05aa50bc30

One decision. A different kind of result.

A single formulation designed to work at the cellular level, where collagen is formed, where inflammation is balanced, where skin’s natural processes determine how it evolves over time.

A standard that redefines what consistency can achieve.
What's Inside

Every ingredient
earns its place.

Each component is selected for a specific biological function and works in concert with the others.
BioBlend_Technology_b21dcd51-8481-4410-ad0c-588a80b533d1

BioBlend Technology™

Human Mesenchymal Conditioned Media carrying 1,200+ growth factors and 1.2 trillion exosomes — biological signals that communicate directly with your skin's repair mechanisms. The ingredient no competitor has.
honeybee_defensin

Honeybee Defensin-1

A rare antimicrobial peptide that strengthens your skin's natural defenses, accelerates healing, and reduces the inflammation that silently accelerates visible aging. Your skin becomes more resilient — not just more treated.
niacinomide

High-Powered Peptide Complex

A curated selection of biomimetic peptides that instruct your skin to produce collagen and elastin — the structural proteins responsible for firmness, elasticity, and the texture that signals youth.
Keratinocyte_Growth_Factor

Keratinocyte Growth Factor

Accelerates the skin's natural renewal cycle. Barrier strength improves. Recovery from environmental stress shortens. Skin behaves younger — not because it's been temporarily plumped, but because its foundational cells are functioning better.
carnosine

Carnosine

Guards against glycation — the sugar-driven collagen damage that stiffens and dulls skin over time. One of the most clinically significant anti-aging mechanisms, rarely addressed at this potency in consumer formulations.
vitaminc

Tetrahexyldecyl Ascorbate

The stable, oil-soluble Vitamin C that actually penetrates the dermis. Stimulates collagen synthesis, corrects uneven tone, defends against oxidative damage — without the instability that degrades standard Vitamin C on the shelf.
niacinamide

Niacinamide

Reduces redness, strengthens the moisture barrier, and brightens skin tone — working in concert with the growth factors to support an environment where cellular repair can occur without chronic inflammatory interference.
Sodium_Hyaluronate

Sodium Hyaluronate

Deep hydration at the dermal level — not just surface moisture. Plumps the skin's architecture so that cellular repair happening below is supported by a structurally sound, well-hydrated environment above it.

The All-in-One Anti-Aging Formulation

1,200+

growth factors, proteins, and peptides

1.2+ Trillion

exosomes

Clinically Supported, Physician Approved

Our team of leading PhDs, with over five decades of clinical research experience, utilize proprietary scientific methods to pioneer our advanced technology.

Independent third-party clinical trials suggest that BioBlend Technology™ sets a new standard in skincare and hair restoration, offering one of the most potent and effective ingredients on the market.
Rejuvenating-Complex-Serum-Bottle
INVO-Anti-Aging-Serum-2
invo-slide1

Clinically Supported, Physician Approved

Our team of leading PhDs, with over five decades of clinical research experience, utilize proprietary scientific methods to pioneer our advanced technology.

Independent third-party clinical trials suggest that BioBlend Technology™ sets a new standard in skincare and hair restoration, offering one of the most potent and effective ingredients on the market.
Clinical Observation
Results you can see.
Science you can trust.
Real patients. Real timelines. No filters, no retouching. The results below represent documented outcomes from clinical use. Our full results study is ongoing and will be updated as data is collected.
before-after-2
Before
After
before-after-1

Radiance, fine line reduction

73-year-old patient · RC only, twice daily · No treatments · 8 weeks

before-after-2
Before
After
before-after-1

Dark spot reduction, even tone

2 treatments · Microneedling + INVO Brightening + Rejuvenating Complex Daily · 8 weeks

before-after-2
Before
After
before-after-1

Visible firmness, texture refinement

2 treatments · Microneedling + Rejuvenating Complex · 8 weeks

before-after-2
Before
After
before-after-1

Redness reduction, texture refinement, even tone

2 Moxi treatments · Brightening Skin Solutions + Rejuvenating Complex · 8 weeks

From the People Using It
What it feels like
to stop searching.
Common Questions
Everything you need
to decide with confidence.

Are your products safe for all skin types?

Our formulations are designed to be effective yet gentle. However, we recommend reviewing the ingredient list and performing a patch test if you have sensitive skin.

How do I use the Rejuvenating Complex in my skincare routine?

Apply a few drops to clean, dry skin in the morning and evening before moisturizer. For best results, use consistently as part of your daily regimen.

What makes Rejuvenating Complex different from other growth factor serums?

Rejuvenating Complex is powered by BioBlend Technology™, a proprietary process that combines growth factors, peptides, and exosomes from multiple sources. This creates a more robust and effective formula compared to single-source growth factor serums.

Is it safe for sensitive skin?

Yes. The formula is designed for all skin types, including sensitive and post-procedure skin. If you are new to growth factors or exosome-based skincare, start by applying once daily before increasing to twice daily.

Can I use Rejuvenating Complex after in-office treatments?

Yes. Many professionals recommend using Rejuvenating Complex after treatments such as microneedling, lasers, or chemical peels to help support recovery and enhance results. Always consult your provider for personalized instructions.